USP11 controls R-loops by regulating senataxin proteostasis
Yes === R-loops are by-products of transcription that must be tightly regulated to maintain genomic stability and gene expression. Here, we describe a mechanism for the regulation of the Rloop- specific helicase, senataxin (SETX), and identify the ubiquitin specific peptidase 11 (USP11) as an R-l...
| Main Authors: | , , , |
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| Language: | en |
| Published: |
2021
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10454/18592 |