Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

Yes === pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell carcinoma) has the most serious outcome due to its resistance to chemotherapies and radiotherapies. Although HIF promotes the progression of ccRCC, the precise mechanism by...

Full description

Bibliographic Details
Main Authors: Kim, H.R., Santhakumar, K., Markham, E., Baldera, D., Greenald, D., Bryant, H.E., El-Khamisy, Sherif F., van Eeden, F.J.
Language:en
Published: 2020
Subjects:
Hif
Vhl
DNA repair
Apoptosis
Chemo/radio-resistance
Online Access:http://hdl.handle.net/10454/18019

Internet

http://hdl.handle.net/10454/18019

Similar Items