Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer
Yes === Purpose: Despite positive responses in phase II clinical trials, the bioreductive prodrug apaziquone failed to achieve statistically significant activity in non-muscle invasive bladder cancer in phase III trials. Apaziquone was administered shortly after transurethral resection and here we...
Main Authors: | Phillips, Roger M., Loadman, Paul M., Reddy, G. |
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Language: | en |
Published: |
2019
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Subjects: | |
Online Access: | http://hdl.handle.net/10454/17119 |
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