Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer

Yes === Purpose: Despite positive responses in phase II clinical trials, the bioreductive prodrug apaziquone failed to achieve statistically significant activity in non-muscle invasive bladder cancer in phase III trials. Apaziquone was administered shortly after transurethral resection and here we...

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Bibliographic Details
Main Authors: Phillips, Roger M., Loadman, Paul M., Reddy, G.
Language:en
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10454/17119

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