MicroRNA‐21 drives the switch to a synthetic phenotype in human saphenous vein smooth muscle cells

MicroRNA‐21 drives the switch to a synthetic phenotype in human saphenous vein smooth muscle cells

Yes === Cardiovascular disease is a leading cause of morbidity and mortality. Smooth muscle cells (SMC) comprising the vascular wall can switch phenotypes from contractile to synthetic, which can promote the development of aberrant remodelling and intimal hyperplasia (IH). MicroRNA‐21 (miR‐21) is a...

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Bibliographic Details
Main Authors: Alshanwani, A.R., Riches-Suman, Kirsten, O'Regan, D.J., Wood, I.C., Turner, N.A., Porter, K.E.
Language:en
Published: 2018
Subjects:
MicroRNA-21
Platelet-derived growth factor
Saphenous vein
Smooth muscle cell
Phenotype
Remodeling
Online Access:http://hdl.handle.net/10454/16246

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