Synthesis of Zeolitic Imidazolate Framework-8-Based Nanocomposites and Applications

• Main Author: Zhuang, Jia
• Format: Others
• Language: English
• Published: Boston College 2015
• Subjects: Drug Delivery; Heterogenous Catalysis; Metal-Organic Framework; Zeolitic Imidazolate Framework-8
• Online Access: http://hdl.handle.net/2345/bc-ir:104169

Thesis advisor: Chia-Kuang Tsung === Thesis advisor: Eranthie Weerapana === Metal-Organic Frameworks (MOFs) are crystalline porous materials constructed of metal ions and organic linkers, and have been widely utilized in gas storage, sensing, and chromatographic separation. The combination of MOF nanoparticles with other materials will broaden the utilization of MOF materials to a great extent. Several approaches for creating composites with the MOF, Zeolitic Imidazolate Framework-8 (ZIF-8), have been developed: dye and model drug molecules were encapsulated in ZIF-8 pores for potential drug delivery; mesoporous silica monolayer was epitaxially grown on the ZIF-8 surface for structural stability enhancement and hollow structure formation; UiO-66, another MOF subclass, was hierarchically encased inside ZIF-8 for double-phase gas separation and heterogeneous catalysis. By exploring the versatile ZIF-8 platform, these nanocomposites could have great applications in fields such as heterogeneous catalysis and drug delivery. === Thesis (MS) — Boston College, 2015. === Submitted to: Boston College. Graduate School of Arts and Sciences. === Discipline: Chemistry.