Monitoring Allosteric Effector Binding and Homotropic Cooperativity of Aspartate Transcarbamoylase

Thesis advisor: Evan Kantrowitz === Aspartate transcarbamoylase (ATCase) catalyzes the reaction between carbamoyl phosphate (CP) and aspartate to form N-carbamoyl-L-aspartate (CA) and inorganic phosphate (Pi). In Escherichia coli, it catalyzes the committed step of pyrimidine nucleotide biosy...

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Bibliographic Details
Main Author: Martinez, Jessica
Format: Others
Language:English
Published: Boston College 2008
Subjects:
Online Access:http://hdl.handle.net/2345/1359