Contribution au développement de nouveaux vecteurs inductibles par la tétracycline et basés sur le parvovirus adéno-associé (AAV)

Contribution au développement de nouveaux vecteurs inductibles par la tétracycline et basés sur le parvovirus adéno-associé (AAV)

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Le parvovirus adéno-associé (AAV) possède un génome à ADN linéaire simple brin de 4,7kb encadré par deux séquences palindromiques inversées et identiques de 145 nucléotides appelées ITRs, requises en cis pour la réplication et l’encapsidation de l’ADN viral. Dans un AAV recombinant (rAAV), la totali...

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Bibliographic Details
Main Author:	Chtarto, Abdelwahed
Other Authors:	De Kerchove, Alban
Format:	Others
Language:	fr
Published:	Universite Libre de Bruxelles 2005
Subjects:	Striatum Tet-On Thérapie génique AAV Tétracycline Globus Pallidus Vecteur autorégulable WPRE GDNF Minocycline Parkinson Doxycycline
Online Access:	http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-10092005-205152/

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