Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma/Induction à long terme d’une tolérance spécifique de l’antigène dans un modèle murin d’asthme expérimental en administrant des cellules dendritiques génétiquement modifiées sécrétant de l’IL-10
Résumé Dendritic cells (DCs) are professional APCs that have a unique capacity to initiate primary immune responses, including tolerogenic responses. We have genetically engineered bone marrow-derived DCs to express the immunosuppressive cytokine IL-10 and tested the ability of these cells to contro...
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| Format: | Others |
| Language: | fr |
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Universite Libre de Bruxelles
2007
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| Online Access: | http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-07162009-162949/ |