Role of nitric oxide and viral products in pancreatic beta-cell dysfunction and death

SUMMARY Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by progressive destruction of insulin-producing pancreatic beta-cells. Both viral infections and the cytokines interleukin-1beta (IL-1beta) and interferon-gamma (IFN-gamma) have been suggested as potential mediators of beta-cell...

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Bibliographic Details
Main Author: Liu, Dongbo
Other Authors: Welsh Nils
Format: Others
Language:en
Published: Universite Libre de Bruxelles 2004
Subjects:
Online Access:http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-02202004-104201/