Galectin-1 Improves Sarcolemma Repair and Decreases the Inflammatory Response in LGMD2B Models

Galectin-1 Improves Sarcolemma Repair and Decreases the Inflammatory Response in LGMD2B Models

Limb-girdle muscular dystrophy type 2B (LGMD2B) is caused by mutations in the dysferlin gene, resulting in non-functional dysferlin, a key protein found in muscle membrane. Treatment options available for patients are chiefly palliative in nature and focus on maintaining ambulation. Our hypothesis i...

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Bibliographic Details
Main Author: Rathgeber, Matthew F.
Format: Others
Published: BYU ScholarsArchive 2020
Subjects:
Muscular Dystrophy
LGMD2B
Dysferlinopathy
Galectin-1
NF-κB
inflammation
Macrophage polarization
M2
cyto-regenerative
Physical Sciences and Mathematics
Online Access:https://scholarsarchive.byu.edu/etd/8723
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=9723&context=etd

Internet

https://scholarsarchive.byu.edu/etd/8723
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=9723&context=etd

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