Bifunctional Helical Peptide Catalysts for Enzyme-like Reactivity and Selectivity and Selective Stapling of Natural Amino Acid Residues with Hydrophilic Squaric Acid Derivatives
Peptide secondary structure provides an exceptional scaffold on which to design highly reactive and selective enzyme-like catalysts. This work describes the rational design and synthesis of a suite of helical peptide catalysts that are capable of achieving proximity-induced rate enhancement in Diels...
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| Format: | Others |
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BYU ScholarsArchive
2019
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| Online Access: | https://scholarsarchive.byu.edu/etd/8714 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=9714&context=etd |