CRISPR-Cas9 Transfection Optimization and Use in a Forward Genetic Screen to Identify Telomere Length Maintenance Genes

Mutations in the telomere length maintenance pathway can lead to a spectrum of diseases called telomere syndromes, however, the pathway is not fully understood and there may still be unknown components. We designed a forward genetic screen to identify new genes involved in telomere length maintenanc...

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Bibliographic Details
Main Author: Phillips, Kelsey
Format: Others
Published: BYU ScholarsArchive 2018
Subjects:
Online Access:https://scholarsarchive.byu.edu/etd/7357
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8357&context=etd