Blockade of TGF-ß Signaling Through the Activin Type IIB Receptor with the Small Molecule, SGI-1252
Antagonism of the activin receptor signaling pathway represents a promising potential therapy for the muscular dystrophies and other muscle wasting disorders (i.e., cachexia or sarcopenia). Previous research has shown that antagonism of activin signaling promotes muscle growth, attenuates muscle was...
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| Format: | Others |
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BYU ScholarsArchive
2015
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| Online Access: | https://scholarsarchive.byu.edu/etd/6125 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7125&context=etd |