Palladium-Catalyzed Intramolecular C-H Difluoroalkylation: Synthesis of Substituted 3,3-Difluoro-2-oxindoles
The synthesis of 3,3-difluoro-2-oxindoles through a robust and efficient palladium-catalyzed C-H difluoroalkylation is described. This process generates a broad range of difluorooxindoles from readily prepared starting materials. The use of BrettPhos as the ligand was crucial for high efficiency. Pr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley Blackwell,
2015-11-03T12:53:55Z.
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| Subjects: | |
| Online Access: | Get fulltext |