An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants

The oxidation of guanine to 8-oxo-2'-deoxyguanosine (8-oxo-dG) is one of the most abundant and best studied oxidative DNA lesions and is commonly used as a biomarker for oxidative stress. Over the last decades, various methods for the detection of DNA oxidation products have been established an...

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Bibliographic Details
Main Authors: Moreno-Villanueva, Maria (Author), Fischbach, Arthur (Author), Martello, Rita (Author), Dedon, Peter C. (Contributor), Ullrich, Volker (Author), Mangerich, Aswin (Contributor), Muller, Nathalie (Author), Kienhofer, Joachim (Author), Burkle, Alexander (Author)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-10-15T12:58:18Z.
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