Translocation of Non-Canonical Polypeptides into Cells Using Protective Antigen

Translocation of Non-Canonical Polypeptides into Cells Using Protective Antigen

A variety of pathogenic bacteria infect host eukaryotic cells using protein toxins, which enter the cytosol and exert their cytotoxic effects. Anthrax lethal toxin, for example, utilizes the membrane-spanning translocase, protective antigen (PA) pore, to deliver the protein toxin lethal factor (LF)...

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Bibliographic Details
Main Authors: Rabideau, Amy E. (Contributor), Liao, Xiaoli (Contributor), Akcay, Gizem (Contributor), Pentelute, Bradley L. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-09-10T16:13:17Z.
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