Impact of kinesin Eg5 inhibition by 3,4-dihydropyrimidin-2(1H)-one derivatives on various breast cancer cell features

Impact of kinesin Eg5 inhibition by 3,4-dihydropyrimidin-2(1H)-one derivatives on various breast cancer cell features

Background Breast cancer is a complex heterogeneous disease and is one of the leading causes of death among women. In addressing the need for treatments of this life-threatening illness, we studied 3,4-dihydropyrimidin-2(1H)-one (or thione) derivatives (DHPMs), a class of inhibitor molecules of the...

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Main Authors: Guido, Bruna C (Author), Ramos, Luciana M (Author), Nobrega, Catharine C (Author), Pic-Taylor, Aline (Author), Neto, Brenno AD (Author), Nolasco, Diego (Contributor), Correa, Jose R (Author), Andrade, Barbara YG (Author)
Other Authors: Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2015-06-29T17:23:37Z.
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