Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

The design, synthesis, and characterization of enterobactin-antibiotic conjugates, hereafter Ent-Amp/Amx, where the β-lactam antibiotics ampicillin (Amp) and amoxicillin (Amx) are linked to a monofunctionalized enterobactin scaffold via a stable poly(ethylene glycol) linker are reported. Under condi...

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Bibliographic Details
Main Authors:	Zheng, Tengfei (Contributor), Nolan, Elizabeth M. (Contributor)
Other Authors:	Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format:	Article
Language:	English
Published:	American Chemical Society (ACS), 2015-06-22T16:02:48Z.
Subjects:	Article
Online Access:	Get fulltext

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