Visualizing KcsA Conformational Changes upon Ion Binding by Infrared Spectroscopy and Atomistic Modeling

The effect of ion binding in the selectivity filter of the potassium channel KcsA is investigated by combining amide I Fourier-transform infrared spectroscopy with structure-based spectral modeling. Experimental difference IR spectra between K[superscript +]-bound KcsA and Na[superscript +]-bound Kc...

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Bibliographic Details
Main Authors: Stevenson, Paul (Contributor), Baiz, Carlos R. (Author), Akerboom, Jasper (Author), Tokmakoff, Andrei (Author), Vaziri, Alipasha (Author), Gotz, Christoph (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-06-22T15:25:09Z.
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