Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster

Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster

Iron is an essential nutrient for cells. It is unknown how iron, after its import into the cytosol, is specifically delivered to iron-dependent processes in various cellular compartments. Here, we identify an essential function of the conserved cytosolic monothiol glutaredoxins Grx3 and Grx4 in intr...

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Main Authors: Mühlenhoff, Ulrich (Author), Molik, Sabine (Author), Godoy, José R. (Author), Uzarska, Marta A. (Author), Richter, Nadine (Author), Seubert, Andreas (Author), Zhang, Yan (Contributor), Stubbe, JoAnne (Contributor), Pierrel, Fabien (Author), Herrero, Enrique (Author), Lillig, Christopher Horst (Author), Lill, Roland (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-03-17T20:01:20Z.
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