Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice

Women are more resistant to hepatocellular carcinoma (HCC) than men despite equal exposure to major risk factors, such as hepatitis B or C virus infection. Female resistance is hormone-dependent, as evidenced by the sharp increase in HCC incidence in postmenopausal women who do not take hormone repl...

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Bibliographic Details
Main Authors: Hartwell, Hadley J. (Author), Petrosky, Keiko Y. (Author), Fox, James G. (Contributor), Horseman, Nelson D. (Author), Rogers, Arlin B. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-03-04T15:55:33Z.
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Online Access:Get fulltext

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