Calcineurin determines toxic versus beneficial responses to  α-synuclein

Calcineurin determines toxic versus beneficial responses to  α-synuclein

Calcineurin (CN) is a highly conserved Ca[superscript 2+]-calmodulin (CaM)-dependent phosphatase that senses Ca[superscript 2+] concentrations and transduces that information into cellular responses. Ca[superscript 2+] homeostasis is disrupted by α-synuclein (α-syn), a small lipid binding protein wh...

Full description

Bibliographic Details
Main Authors: Caraveo, Gabriela (Contributor), Baru, Valeriya (Contributor), Lindquist, Susan (Contributor), Auluck, Pavan K. (Author), Whitesell, Luke (Author), Chung, Chee Yeun (Author), Mosharov, Eugene V. (Author), Yan, Xiohui (Author), Ben-Johny, Manu (Author), Soste, Martin (Author), Picotti, Paola (Author), Kim, Hanna (Author), Caldwell, Kim A. (Author), Caldwell, Guy A. (Author), Sulzer, David (Author), Yue, David T. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-03-03T19:18:43Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items