Rapid and Efficient Trifluoromethylation of Aromatic and Heteroaromatic Compounds Using Potassium Trifluoroacetate Enabled by a Flow System
The trifluoromethylation of aryl/heteroaryl iodides has been demonstrated using a flow system, thus enabling a rapid rate of reaction. A broad spectrum of trifluoromethylated compounds was prepared in good to excellent yields using CF[subscript 3]CO[subscript 2]K as the trifluoromethyl source. The p...
Main Authors: | Chen, Mao (Contributor), Buchwald, Stephen Leffler (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley Blackwell,
2015-02-06T20:03:01Z.
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Subjects: | |
Online Access: | Get fulltext |
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