Synthesis and Application of Palladium Precatalysts that Accommodate Extremely Bulky Di-tert-butylphosphino Biaryl Ligands

A series of palladacyclic precatalysts that incorporate electron-rich di-tert-butylphosphino biaryl ligands is reported. These precatalysts are easily prepared, and their use provides a general means of employing bulky ligands in palladium-catalyzed cross-coupling reactions. The application of these...

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Bibliographic Details
Main Authors: Bruno, Nicholas C. (Contributor), Buchwald, Stephen Leffler (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-02-06T19:56:45Z.
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Online Access:Get fulltext
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100 1 0 |a Bruno, Nicholas C.  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Chemistry  |e contributor 
100 1 0 |a Bruno, Nicholas C.  |e contributor 
100 1 0 |a Buchwald, Stephen Leffler  |e contributor 
700 1 0 |a Buchwald, Stephen Leffler  |e author 
245 0 0 |a Synthesis and Application of Palladium Precatalysts that Accommodate Extremely Bulky Di-tert-butylphosphino Biaryl Ligands 
260 |b American Chemical Society (ACS),   |c 2015-02-06T19:56:45Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/93913 
520 |a A series of palladacyclic precatalysts that incorporate electron-rich di-tert-butylphosphino biaryl ligands is reported. These precatalysts are easily prepared, and their use provides a general means of employing bulky ligands in palladium-catalyzed cross-coupling reactions. The application of these palladium sources to various C-N and C-O bond-forming processes is also described. 
520 |a National Institutes of Health (U.S.) (GM58160) 
520 |a National Institutes of Health (U.S.) (GM46059) 
520 |a Amgen Inc. 
546 |a en_US 
655 7 |a Article 
773 |t Organic Letters