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92948 |
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|a Yang, Lu
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|a Massachusetts Institute of Technology. Department of Chemical Engineering
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|a Jensen, Klavs F.
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|a Yang, Lu
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|a Jensen, Klavs F.
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|a Jensen, Klavs F.
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|a Mass Transport and Reactions in the Tube-in-Tube Reactor
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|b American Chemical Society (ACS),
|c 2015-01-16T19:17:23Z.
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|z Get fulltext
|u http://hdl.handle.net/1721.1/92948
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|a The tube-in-tube reactor is a convenient method for implementing gas/liquid reactions on the microscale, in which pressurized gas permeates through a Teflon AF-2400 membrane and reacts with substrates in liquid phase. Here we present the first quantitative models for analytically and numerically computing gas and substrate concentration profiles within the tube-in-tube reactor. The model accurately predicts mass transfer performance in good agreement with experimental measurement. The scaling behavior and reaction limitations of the tube-in-tube reactor are predicted by modeling and compared with gas/liquid micro- and minireactors. The presented model yields new insights into the scalability and applicability of the tube-in-tube reactor.
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|a Novartis-MIT Center for Continuous Manufacturing
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|a en_US
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|a Article
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|t Organic Process Research & Development
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