Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

Microcephaly is a neurodevelopmental disorder causing significantly reduced cerebral cortex size. Many known microcephaly gene products localize to centrosomes, regulating cell fate and proliferation. Here, we identify and characterize a nuclear zinc finger protein, ZNF335/NIF-1, as a causative gene...

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Bibliographic Details
Main Authors: Baltus, Andrew E. (Author), Mathew, Rebecca S (Author), Murphy, Elisabeth A. (Author), Evrony, Gilad D (Author), Gonzalez, Dilenny M (Author), Wang, Estee P (Author), Marshall-Walker, Christine A (Author), Barry, Brenda J (Author), Murn, Jernej (Author), Tatarakis, Antonis (Author), Mahajan, Muktar A (Author), Samuels, Herbert H (Author), Shi, Yang (Author), Golden, Jeffrey A (Author), Mahajnah, Muhammad (Author), Shenhav, Ruthie (Author), Walsh, Christopher A (Author), Yang, Yawei (Contributor)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-12T13:11:59Z.
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