CRISPRseek: A Bioconductor Package to Identify Target-Specific Guide RNAs for CRISPR-Cas9 Genome-Editing Systems
CRISPR-Cas systems are a diverse family of RNA-protein complexes in bacteria that target foreign DNA sequences for cleavage. Derivatives of these complexes have been engineered to cleave specific target sequences depending on the sequence of a CRISPR-derived guide RNA (gRNA) and the source of the Ca...
Main Authors: | Zhu, Lihua J. (Author), Holmes, Benjamin Ray (Contributor), Aronin, Neil (Author), Brodsky, Michael H. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2014-10-20T17:25:18Z.
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Subjects: | |
Online Access: | Get fulltext |
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