A beamforming approach to phase-amplitude modulation analysis of multi-channel EEG

Phase-amplitude modulation is a form of cross frequency coupling where the phase of one frequency influences the amplitude of another higher frequency. It has been observed in neurophysiological recordings during sensory, motor, and cognitive tasks, as well as during general anesthesia. In this pape...

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Bibliographic Details
Main Authors: Sampson, A. L. (Author), Mukamel, Eran A. (Author), Babadi, Behtash (Contributor), Prerau, Michael J. (Contributor), Brown, Emery N. (Contributor), Purdon, Patrick Lee (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: Institute of Electrical and Electronics Engineers (IEEE), 2014-05-01T13:57:55Z.
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Online Access:Get fulltext
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100 1 0 |a Sampson, A. L.  |e author 
100 1 0 |a Harvard University-  |e contributor 
100 1 0 |a Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences  |e contributor 
100 1 0 |a Babadi, Behtash  |e contributor 
100 1 0 |a Prerau, Michael J.  |e contributor 
100 1 0 |a Brown, Emery N.  |e contributor 
100 1 0 |a Purdon, Patrick Lee  |e contributor 
700 1 0 |a Mukamel, Eran A.  |e author 
700 1 0 |a Babadi, Behtash  |e author 
700 1 0 |a Prerau, Michael J.  |e author 
700 1 0 |a Brown, Emery N.  |e author 
700 1 0 |a Purdon, Patrick Lee  |e author 
245 0 0 |a A beamforming approach to phase-amplitude modulation analysis of multi-channel EEG 
260 |b Institute of Electrical and Electronics Engineers (IEEE),   |c 2014-05-01T13:57:55Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/86316 
520 |a Phase-amplitude modulation is a form of cross frequency coupling where the phase of one frequency influences the amplitude of another higher frequency. It has been observed in neurophysiological recordings during sensory, motor, and cognitive tasks, as well as during general anesthesia. In this paper, we describe a novel beamforming procedure to improve estimation of phase-amplitude modulation. We apply this method to 64-channel EEG data recorded during propofol general anesthesia. The method improves the sensitivity of phase-amplitude analyses, and can be applied to a variety of multi-channel neuroscience data where phase-amplitude modulation is present. 
520 |a National Institutes of Health (U.S.) (Grant DP2-OD006454) 
520 |a National Institutes of Health (U.S.) (Grant K25-NS057580) 
520 |a National Institutes of Health (U.S.) (Grant DP1-OD003646) 
520 |a National Institutes of Health (U.S.) (Grant R01-EB006385) 
546 |a en_US 
655 7 |a Article 
773 |t Proceedings of the 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society