Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia

Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia

Purpose: The disease course of chronic lymphocytic leukemia (CLL) varies significantly within cytogenetic groups. We hypothesized that high-resolution genomic analysis of CLL would identify additional recurrent abnormalities associated with short time-to-first therapy (TTFT). Experimental Design: We...

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Main Authors: Brown, Jennifer R. (Author), Hanna, Megan (Author), Tesar, Bethany (Author), Werner, Lillian (Author), Pochet, Nathalie (Author), Asara, John M. (Author), Wang, Yaoyu E. (Author), dal Cin, Paola (Author), Fernandes, Stacey M. (Author), Thompson, Christina (Author), MacConaill, Laura (Author), Wu, Catherine J. (Author), Van de Peer, Yves (Author), Correll, Mick (Author), Regev, Aviv (Contributor), Neuberg, Donna S. (Author), Freedman, Arnold S. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research, 2014-02-21T18:03:41Z.
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