Optical control of neuronal excitation and inhibition using a single opsin protein, ChR2

The effect of electrical stimulation on neuronal membrane potential is frequency dependent. Low frequency electrical stimulation can evoke action potentials, whereas high frequency stimulation can inhibit action potential transmission. Optical stimulation of channelrhodopsin-2 (ChR2) expressed in ne...

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Bibliographic Details
Main Authors: Liske, Holly (Author), Qian, Xiang (Author), Deisseroth, Karl (Author), Delp, Scott (Author), Anikeeva, Polina Olegovna (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-02-19T17:40:29Z.
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