Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression
In metazoans, how replication origins are specified and subsequently activated is not well understood. Drosophila amplicons in follicle cells (DAFCs) are genomic regions that undergo rereplication to increase DNA copy number. We identified all DAFCs by comparative genomic hybridization, uncovering t...
Main Authors: | Kim, Jane C. (Contributor), Nordman, Jared T. (Contributor), Orr-Weaver, Terry L. (Contributor), Kashevsky, Helena (Author), Eng, Thomas (Author), Li, Sharon (Author), MacAlpine, David M. (Author), Xie, Fang, Ph. D. Massachusetts Institute of Technology (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Xie, Fang (Contributor) |
Format: | Article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory Press,
2014-02-14T14:27:43Z.
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Subjects: | |
Online Access: | Get fulltext |
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