Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression

Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression

In metazoans, how replication origins are specified and subsequently activated is not well understood. Drosophila amplicons in follicle cells (DAFCs) are genomic regions that undergo rereplication to increase DNA copy number. We identified all DAFCs by comparative genomic hybridization, uncovering t...

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Bibliographic Details
Main Authors: Kim, Jane C. (Contributor), Nordman, Jared T. (Contributor), Orr-Weaver, Terry L. (Contributor), Kashevsky, Helena (Author), Eng, Thomas (Author), Li, Sharon (Author), MacAlpine, David M. (Author), Xie, Fang, Ph. D. Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Xie, Fang (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2014-02-14T14:27:43Z.
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