Histone H3K27ac separates active from poised enhancers and predicts developmental state

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Developmental programs are controlled by transcription factors and chromatin regulators, which maintain specific gene expression programs through epigenetic modification of the genome. These regulatory events at enhancers contribute to the specific gene expression programs that determine cell state...

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Bibliographic Details
Main Authors: Creyghton, Menno P. (Author), Cheng, Albert W. (Contributor), Welstead, G. Grant (Author), Kooistra, Tristan G. (Contributor), Carey, Bryce W. (Contributor), Steine, Eveline J. (Contributor), Hanna, Jacob (Author), Lodato, Michael Anthony (Contributor), Frampton, Garrett M. (Contributor), Sharp, Phillip A. (Contributor), Boyer, Laurie (Contributor), Young, Richard A. (Contributor), Jaenisch, Rudolf (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-01-27T17:58:12Z.
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