CYSL-1 Interacts with the O[subscript 2]-Sensing Hydroxylase EGL-9 to Promote H[subscript 2]S-Modulated Hypoxia-Induced Behavioral Plasticity in C. elegans

CYSL-1 Interacts with the O[subscript 2]-Sensing Hydroxylase EGL-9 to Promote H[subscript 2]S-Modulated Hypoxia-Induced Behavioral Plasticity in C. elegans

The C. elegans HIF-1 proline hydroxylase EGL-9 functions as an O[subscript 2] sensor in an evolutionarily conserved pathway for adaptation to hypoxia. H[subscript 2]S accumulates during hypoxia and promotes HIF-1 activity, but how H[subscript 2]S signals are perceived and transmitted to modulate HIF...

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Bibliographic Details
Main Authors:	Vozdek, Roman (Author), Bhatla, Nikhil (Contributor), Ma, Dengke (Contributor), Horvitz, Howard Robert (Author)
Other Authors:	Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Horvitz, H. Robert (Contributor)
Format:	Article
Language:	English
Published:	Elsevier, 2014-01-24T19:21:23Z.
Subjects:	Article
Online Access:	Get fulltext

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