DNA Sequence Preferences of Transcriptional Activators Correlate More Strongly than Repressors with Nucleosomes

DNA Sequence Preferences of Transcriptional Activators Correlate More Strongly than Repressors with Nucleosomes

Transcription factors (TFs) and histone octamers are two abundant classes of DNA binding proteins that coordinate the transcriptional program in cells. Detailed studies of individual TFs have shown that TFs bind to nucleosome-occluded DNA sequences and induce nucleosome disruption/repositioning, whi...

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Bibliographic Details
Main Authors: Charoensawan, Varodom (Author), Janga, Sarath Chandra (Author), Bulyk, Martha L. (Contributor), Babu, M. Madan (Author), Teichmann, Sarah A (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier, 2013-11-18T15:18:57Z.
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