Preparation of Mammalian Expression Vectors Incorporating Site-Specifically Platinated-DNA Lesions
FDA-approved platinum-based anticancer drugs, cisplatin, carboplatin, and oxaliplatin, are some of the most effective chemotherapies in clinical use. The cytotoxic action of these compounds against cancer requires a combination of processes including cell entry, drug activation, DNA binding, and tra...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2013-11-18T13:34:42Z.
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| Subjects: | |
| Online Access: | Get fulltext |