Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site

Replacement of a single dA nucleotide positioned at a programmed site in a DNA plasmid with its 7-deaza-analog is described together with its complete resistance to restriction enzymatic cleavage.

Bibliographic Details
Main Authors: Ang, Wee Han (Contributor), Lippard, Stephen J. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2013-11-15T19:04:17Z.
Subjects:
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