A General Method for Suzuki-Miyaura Coupling Reactions Using Lithium Triisopropyl Borates

A General Method for Suzuki-Miyaura Coupling Reactions Using Lithium Triisopropyl Borates

Conditions for the Suzuki-Miyaura coupling of lithium triisopropyl borates are reported, as well as a procedure for a one-pot lithiation, borylation, and subsequent Suzuki-Miyaura coupling of various heterocycles with aryl halides. These borate species are much more stable toward protodeboronation t...

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Bibliographic Details
Main Authors: Buchwald, Stephen Leffler (Contributor), Oberli, Matthias (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2013-11-01T17:08:40Z.
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