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01348 am a22002053u 4500 |
| 001 |
80328 |
| 042 |
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|a dc
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| 100 |
1 |
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|a Kim, Jun Ki
|e author
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| 100 |
1 |
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|a Harvard University-
|e contributor
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| 100 |
1 |
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|a Yun, Seok Hyun
|q (Andy)
|e contributor
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| 700 |
1 |
0 |
|a Yun, Seok Hyun
|q (Andy)
|e author
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| 700 |
1 |
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|a Choi, Jin Woo
|e author
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| 245 |
0 |
0 |
|a 350-μm side-view optical probe for imaging the murine brain in vivo from the cortex to the hypothalamus
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| 260 |
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|b SPIE,
|c 2013-08-30T15:04:18Z.
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| 856 |
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|z Get fulltext
|u http://hdl.handle.net/1721.1/80328
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| 520 |
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|a Miniature endoscopic probes offer a solution for deep brain imaging by overcoming the limited depth of intravital microscopy. We describe a small-diameter (350 μm) graded-index optical probe with a side-view design for in vivo cellular imaging of the mammalian brain. The side-view probe provides a unique view of the vertical network of neurons and penetrating blood vessels. At a given insertion site, the translational and rotational scanning of the probe provides access to a large tissue area (>1 mm[superscript 2]) across the cortex, hippocampus, thalamus, and hypothalamus.
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| 520 |
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|a United States. Dept. of Defense (Grant FA9550-10-1-0537)
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| 546 |
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|a en_US
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| 655 |
7 |
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|a Article
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| 773 |
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|t Journal of Biomedical Optics
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