Measuring Cation Dependent DNA Polymerase Fidelity Landscapes by Deep Sequencing

High-throughput recording of signals embedded within inaccessible micro-environments is a technological challenge. The ideal recording device would be a nanoscale machine capable of quantitatively transducing a wide range of variables into a molecular recording medium suitable for long-term storage...

Full description

Bibliographic Details
Main Authors: Zamft, Bradley Michael (Author), Marblestone, Adam Henry (Author), Kording, Konrad P. (Author), Schmidt, Daniel (Contributor), Tyo, Keith (Author), Church, George M. (Author), Martin Alarcon, Daniel Alberto (Author), Boyden, Edward (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Program in Media Arts and Sciences (Massachusetts Institute of Technology) (Contributor), Martin Alarcon, Daniel Albert (Contributor), Boyden, Edward Stuart (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-08-22T13:22:31Z.
Subjects:
Online Access:Get fulltext