FRET-Labeled siRNA Probes for Tracking Assembly and Disassembly of siRNA-Nanocomplexes

FRET-Labeled siRNA Probes for Tracking Assembly and Disassembly of siRNA-Nanocomplexes

The assembly, stability, and timely disassembly of short interfering RNA (siRNA) nanocomplexes have the potential to affect the efficiency of siRNA delivery and gene silencing. As such, the design of new probes that can measure these properties without significantly perturbing the nanocomplexes or t...

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Bibliographic Details
Main Authors: Alabi, Christopher A. (Contributor), Love, Kevin T. (Contributor), Sahay, Gaurav (Contributor), Stutzman, Tina M. (Contributor), Young, Whitney T. (Author), Langer, Robert (Contributor), Anderson, Daniel Griffith (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Alabi, Christopher Akinleye (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2013-07-02T16:15:16Z.
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