Self-Assembled Gold Nanoparticle Molecular Probes for Detecting Proteolytic Activity

Target-activatable fluorogenic probes based on gold nanoparticles (AuNPs) functionalized with self-assembled heterogeneous monolayers of dye-labeled peptides and poly(ethylene glycol) have been developed to visualize proteolytic activity in vivo. A one-step synthesis strategy that allows simple gene...

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Bibliographic Details
Main Authors: Mu, C. Jenny (Contributor), LaVan, David A. (Author), Langer, Robert (Contributor), Zetter, Bruce R. (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2013-06-06T19:42:57Z.
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