Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA
A major physiologic sign in Parkinson disease is the occurrence of abnormal oscillations in cortico-basal ganglia circuits, which can be normalized by l-DOPA therapy. Under normal circumstances, oscillatory activity in these circuits is modulated as behaviors are learned and performed, but how dopam...
Main Authors: | Lemaire, Nune (Contributor), Ledia, F. Hernandez (Contributor), Hu, Dan (Contributor), Kubota, Yasuo (Contributor), Howe, Mark William (Contributor), Graybiel, Ann M. (Contributor) |
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Other Authors: | McGovern Institute for Brain Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2013-05-14T13:40:08Z.
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Subjects: | |
Online Access: | Get fulltext |
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