Sequence-dependent sliding kinetics of p53

Sequence-dependent sliding kinetics of p53

Proper timing of gene expression requires that transcription factors (TFs) efficiently locate and bind their target sites within a genome. Theoretical studies have long proposed that one-dimensional sliding along DNA while simultaneously reading its sequence can accelerate TF's location of targ...

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Bibliographic Details
Main Authors: Leith, Jason S. (Author), Tafvizi, Anahita (Author), Huang, Fang (Author), Uspal, William Eric (Contributor), Fersht, Alan R. (Author), Oijen, Antoine M. van (Author), Doyle, Patrick S (Author), Mirny, Leonid A (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Massachusetts Institute of Technology. School of Engineering (Contributor), Doyle, Patrick S. (Contributor), Mirny, Leonid A. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2013-02-28T17:10:38Z.
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