Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease
Chromosomal translocations are frequent features of cancer genomes that contribute to disease progression. These rearrangements result from formation and illegitimate repair of DNA double-strand breaks (DSBs), a process that requires spatial colocalization of chromosomal breakpoints. The "conta...
| Main Authors: | , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science,
2013-01-28T14:59:30Z.
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| Subjects: | |
| Online Access: | Get fulltext |