Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

Receptor-mediated apoptosis proceeds via two pathways: one requiring only a cascade of initiator and effector caspases (type I behavior) and the second requiring an initiator-effector caspase cascade and mitochondrial outer membrane permeabilization (type II behavior). Here, we investigate factors c...

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Bibliographic Details
Main Authors: Aldridge, Bree B. (Contributor), Gaudet, Suzanne (Contributor), Lauffenburger, Douglas A. (Contributor), Sorger, Peter K. (Contributor)
Other Authors: Massachusetts Institute of Technology. Cell Decision Process Center (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2013-01-17T17:21:41Z.
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