Identification and characterization of receptor-specific peptides for siRNA delivery

Identification and characterization of receptor-specific peptides for siRNA delivery

Tumor-targeted delivery of siRNA remains a major barrier in fully realizing the therapeutic potential of RNA interference. While cell-penetrating peptides (CPP) are promising siRNA carrier candidates, they are universal internalizers that lack cell-type specificity. Herein, we design and screen a li...

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Bibliographic Details
Main Authors: Ren, Yin (Contributor), Hauert, Sabine (Contributor), Lo, Justin H. (Contributor), Bhatia, Sangeeta N (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Bhatia, Sangeeta N. (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2012-12-10T17:27:03Z.
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