BAY61-3606 Affects the Viability of Colon Cancer Cells in a Genotype-Directed Manner
Background: K-RAS mutation poses a particularly difficult problem for cancer therapy. Activating mutations in K-RAS are common in cancers of the lung, pancreas, and colon and are associated with poor response to therapy. As such, targeted therapies that abrogate K-RAS-induced oncogenicity would be o...
| Main Authors: | , , , , , |
|---|---|
| Other Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science,
2012-10-31T16:49:11Z.
|
| Subjects: | |
| Online Access: | Get fulltext |