Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity
Synthetic biology efforts have largely focused on small engineered gene networks, yet understanding how to integrate multiple synthetic modules and interface them with endogenous pathways remains a challenge. Here we present the design, system integration, and analysis of several large scale synthet...
Main Authors: | Miller, Miles Aaron (Contributor), Hafner, Marc (Contributor), Sontag, Eduardo (Author), Davidsohn, Noah Justin (Contributor), Subramanian, Sairam (Author), Purnick, Priscilla E. M. (Author), Lauffenburger, Douglas A. (Contributor), Weiss, Ron (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor) |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2012-08-29T17:20:26Z.
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Subjects: | |
Online Access: | Get fulltext |
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