Mechanism of the Efficient Tryptophan Fluorescence Quenching in Human γD-Crystallin Studied by Time-Resolved Fluorescence
Human γD-crystallin (HγD-Crys) is a two-domain, β-sheet eye lens protein found in the lens nucleus. Its long-term solubility and stability are important to maintain lens transparency throughout life. HγD-Crys has four highly conserved buried tryptophans (Trps), with two in each of the homologous β-s...
Main Authors: | Chen, Jiejin (Contributor), Toptygin, Dmitri (Author), Brand, Ludwig (Author), King, Jonathan Alan (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2012-07-24T17:56:45Z.
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Subjects: | |
Online Access: | Get fulltext |
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